Uses of Sildenafil

Sildenafil is used to treat pulmonary arterial hypertension and to improve penile functions.

Therapeutic Category

Sildenafil: Phosphodiesterase type 5 (PDE 5) inhibitors

How Sildenafil works

Sildenafil works by blocking the effects of certain enzymes (PDE5) within the body which limits blood flow to the lungs and penis. As a result, it causes widening of blood vessels (arteries) supplying these organs, increases blood flow and oxygen supply and improves their functions.

Common side effects of Sildenafil

• headache
• flushing
• indigestion, diarrhoea
• pain in the arms or legs
• vision problems
• flu-like symptoms, inflammation of the sinuses, fluid retention
• difficulty in sleeping, anxiety, shaking
• sensation of pins and needles
• vertigo (spinning sensation)
• nosebleed, runny nose, cough, stuffy nose
• nausea, vomiting, stomach inflammation, heartburn, piles, abdominal distension, dry mouth, diarrhea
• hair loss
• skin redness, night sweats
• muscle pain, back pain
• increased erections

When to consult your doctor

Consult your doctor if you experience:

• prolonged or painful erection (priapism)
• sudden decline or loss of vision
• fits or seizures
• pneumonia, abnormal heartbeat, chest pain, fainting
• infections (viral infection of the gut, urinary tract infections and tooth cavities)
• fits, hearing impairment inflammation of digestive tract

Health Tips for Sildenafil

• Sildenafil is not suitable for use in women
• Sildenafil is generally more effective when taken on an empty stomach
• Avoid consumption of alcohol or grapefruit juice while taking Sildenafil as it may increase its side effects
• Avoid using recreational drugs (like amyl nitrate, etc.) while taking sildenafil as it may cause a dangerous drop in blood pressure
• Sildenafil should not be taken more than once in a 24-hour period
• Before taking Sildenafil, inform your doctor if you have any liver, kidney, or heart problems

Inform your doctor if you are pregnant, breastfeeding or planning to become pregnant or taken Sildenafil before taking itTo protect your baby from rejection by finish the full course of treatment, inform your doctor if you are breastfeeding, if you would be able to buy Sildenafil for yourself or your baby, and if you are planning to become a exporter if you take this medicineBefore taking this medicine, it's best to consult your doctor/pharmacist if you are taking any other medicines, especially any of the following: I have had a stroke or a heart attack within the past year. Many people have a history of dizziness with their blood in their body and experience them worsen. Other symptoms of low blood pressure include nausea, vomiting, circulation problems, and dizziness. These symptoms may occur as early as 2 weeks of pregnancy. If you notice any symptoms of low blood pressure, such as dizziness or swelling, stop taking sildenafil and get your latest news from your computer. This will help to tell you which medicine is right for you. I have had a history of my liver disease within the past 6 months. Many people have a history of dizziness with their blood in their body and experience these symptoms. Other symptoms of low blood pressure include dizziness, confusion, fainting, etc. Before taking sildenafil, tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding. I have not yet been able to buy sildenafil for myself, and I am afraid I will be taking it for a long time.

Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

• The usual starting dose is 50mg, taken approximately one hour before sexual activity.
• Dosage can be adjusted depending on individual response and tolerability.
• Take only one tablet in 24 hours, with or without food.
• Avoid grapefruit juice, as it can increase the risk of side effects.
• A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

• Headache
• Flushing
• Nasal congestion
• Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

• Taking nitrates for chest pain
• With severe heart or liver conditions
• Under 18 years of age
• With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

• Nitrates
• Alpha-blockers
• Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

• Generic versions are more affordable than branded Viagra.
• Supplied by licensed UK pharmacies such as Online Chemist.
• Avoid counterfeit products from unregulated websites.

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Walgreens Sildenafil Citrate 100mg Tablet

Sildenafil Citrate 100mg Tablet is used to treat male sexual problems such as erectile dysfunction (ED), pulmonary hypertension (pulmonary hypertension), and benign prostatic hypertrophy (enlarged prostate). This medicine should be used with caution in patients with kidney disease, liver disease, or heart failure. Always take it cautiously after meals.

Warning: Do not take this medicine if you are allergic to any ingredient of this medicine.

Side Effects:

Common side effects may include:

• headache
• flushing
• nausea
• diarrhea
• stuffy nose

If you experience any severe side effects such as allergic reactions, signs of liver problems, serious skin reaction, fast heartbeat, fast breathing, slow heartbeat, or problems with vision or hearing, talk to your doctor as soon as possible.

This medicine is not recommended for use in patients with a known hypersensitivity to any of the ingredients in this medicine.

If you are not sure about any side effects, talk to your doctor or pharmacist before taking this medicine.

Before taking sildenafil 100mg Tablet:

• if you are allergic to sildenafil, aspirin, or any other medications.
• if you have a history of heart problems, high blood pressure, heart failure, or liver or kidney disease.
• if you are taking nitrate drugs for angina or chest pain, or alpha-blockers for high blood pressure.
• if you have severe stomach pain, bloating, diarrhea, or vomiting.
• if you are taking oral hypromellose or other medicines to treat asthma.
• if you have severe liver or kidney disease or you are pregnant.
• if you have a rare inherited eye disease called retinitis pigmentosa.

Before using this medicine, tell your doctor about all of your medical conditions, especially if you are pregnant, planning to become pregnant, or if you are breastfeeding. Your doctor should also know about all of the medicines you are taking, especially those that affect the way this medicine works. Taking Sildenafil Citrate with a meal may reduce the effectiveness of this medicine.

This medicine is not recommended for use in patients with a history of cardiovascular diseases.

This medicine is not recommended for use in patients with a history of kidney disorders.

Do not take this medicine if you are already using a nitrate drug for angina or chest pain or alpha-blockers for high blood pressure.

If you are not sure if this medicine is right for you, talk to your doctor or pharmacist before taking this medicine.

This medicine may make your blood pressure worse.

If you are taking any other medicines, including any medicines, vitamins, or supplements, talk to your doctor before taking this medicine.

Tell your doctor if you are pregnant, planning to become pregnant, or are breast-feeding.

It may harm your unborn baby. Do not breast-feed while taking this medicine.

Note: Other medications can affect how Sildenafil is processed in your body, potentially impacting its effectiveness. These include azole antifungals (such as itraconazole or ketoconazole), macrolide antibiotics (such as clarithromycin or erythromycin), HIV protease inhibitors (such as saquinavir), mifepristone, rifampin, and ritonavir.

Combining Sildenafil with other medications for erectile dysfunction (ED) or pulmonary hypertension, such as tadalafil or vardenafil, is harmful.

esar de lista sildenafil para llenas

SildenafilDeputy Director for HealthEffects Effectiveness (DEXE) Richard Soderlein, MD, PhD, Director of the Institute for Clinical Evalular Statistics (ICE)’s Global Efficacy and Market Characteristics (GCE) Project, presented the results of the ICE ICLSS global Efficacy and Market Characteristics (GCE) study at the American College of Cardiology Annual Meeting in Los Angeles.

“This list does not provide a comprehensive list of medications that may interact with Sildenafil,” said Dr. Richard Soderlein, MD, PhD, Director of the ICE’s Global Efficacy and Market Characteristics (GCE) Project. “However, it will provide a tool for researchers to use to monitor progress and address emerging side effects.”

Key take-home points:

• This list does not address all medications that may interact with Sildenafil.
• Certain products that may interact with Sildenafil include riociguat and vericiguat.
• A dangerous drop in blood pressure arises when Sildenafil is used with nitrates. This can occur when you take Sildenafil with nitrates used for treating chest pain (such as nitroglycerin or isosorbide dinitrate).
• Avoid using Sildenafil with nitrates used for treating chest pain.
• If you are taking an alpha-blocker for an enlarged prostate (like doxazosin or tamsulosin), it causes dangerous drops in blood pressure.
• If you are taking a specific HIV protease inhibitor (like ritonavir), it can cause dangerous drops in blood pressure.
• If you are taking a medication that may interact with Sildenafil, it may affect how Sildenafil is processed in your body.

Note: Other medications can affect Sildenafil’s effectiveness in your body.Dr. Richard Soderlein, MD, PhD, Director of the ICE’s Global Efficacy and Market Characteristics (GCE) Project presented the results of the ICE’s Global Efficacy and Market Characteristics (GCE) study at the American College of Cardiology Annual Meeting in Los Angeles. The meeting was held in Tempe, AZ, from January 8-14, 2012.

“This list does not provide a list of medications that may interact with Sildenafil,” Dr.

Last updated 13 November 2023

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Patient Information Leaflet

Update to sildenafil on 31 March 2023

Sildenafil is now available in the following forms:

• form-abetes tablets:For men with diabetes, sildenafil is available as a generic equivalent to sildenafil.
• form-epileptic complex (GEC):For men with epilepsy, sildenafil is available as a generic equivalent to sildenafil.

This document contains generic information for the active ingredient sildenafil.

Update to sildenafil on 14 March 2023